Description

3-[2-[(10R,11S,13S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl]sulfanylpropanoic acid is a high-purity synthetic steroid derivative with a defined stereochemistry, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its precise molecular structure makes it invaluable for the research and development of novel therapeutic agents targeting hormone-related pathways. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in producing sophisticated steroid-based APIs and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel corticosteroid or other steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates targeting nuclear receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC, LC-MS, or NMR.
• Biochemical Research: Employed as a tool compound in biochemical assays to study steroid hormone metabolism, receptor binding, and signal transduction mechanisms.
• Process Chemistry: Utilized for scaling up and optimizing synthetic routes in pilot plants and commercial manufacturing of complex steroid molecules.

Basic Information

Item	Details
Product Name	3-[2-[(10R,11S,13S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl]sulfanylpropanoic acid
CAS No.	114967-88-3
Molecular Formula	C24H34O6S
Molecular Weight	450.59 g/mol
Synonyms	11β,17α,21-Trihydroxy-3,20-dioxo-1,4-pregnadiene-16α-carboxylic Acid, 16α-Carboxy-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione, 16α-Carboxyprednisolone, 16α-Carboxy Prednisolone, Prednisolone-16α-carboxylic Acid, 3-[(11β,17α,21-Trihydroxy-3,20-dioxopregna-1,4-dien-16α-yl)thio]propanoic Acid
EINECS	Contact for details

Quality Control

Our 3-[2-[(10R,11S,13S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl]sulfanylpropanoic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral methods for stereochemical confirmation, and identity verification by IR and NMR. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.