Description

(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-10-[5-hydroxy-4-[(2S)-2-methoxymorpholin-4-yl]-6-methyl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione is a structurally complex anthracycline derivative, a class of compounds renowned for their potent biological activity. This high-purity chemical intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors focused on oncology and antibiotic drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action against cancer cell lines.
• Antibiotic Development: Acts as a precursor in the research and development of new antibiotic compounds.
• Biochemical Tool: Employed as a reference standard or probe in enzymatic and receptor-binding assays.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Academic Research: Supports synthetic organic chemistry and medicinal chemistry programs in university and institutional laboratories.

Basic Information

Item	Detail
Product Name	(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-10-[5-hydroxy-4-[(2S)-2-methoxymorpholin-4-yl]-6-methyl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
CAS No.	108943-08-4
Molecular Formula	C34H41NO14
Molecular Weight	687.69 g/mol
Synonyms	4'-O-Methyl-11-deoxy-13-deoxo-13-(2-methoxymorpholin-4-yl)doxorubicin; 4'-O-Methyl-11-deoxy-13-deoxo-13-(2-methoxymorpholin-4-yl)adriamycin; 4'-O-Methyl-11-deoxy-13-deoxo-13-(2-methoxymorpholin-4-yl)doxorubicinone; 13-(2-Methoxymorpholin-4-yl)-4'-O-methyl-11-deoxy-13-deoxodoxorubicin; A derivative of Doxorubicin; Anthracycline derivative (CAS 108943-08-4); 4'-O-Methyl-11-deoxy-13-deoxo-13-(2-methoxymorpholin-4-yl)-adriamycinone
EINECS	Contact for details

Quality Control

Our (8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-10-[5-hydroxy-4-[(2S)-2-methoxymorpholin-4-yl]-6-methyl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.