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(13α,17S)-12α-[(2-Acetoxy-3-methyl-1-oxopentyl)oxy]-14β,15β:21,23-diepoxy-11β-hydroxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one CAS NO 11052-28-1
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CAS No.:11052-28-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(13α,17S)-12α-[(2-Acetoxy-3-methyl-1-oxopentyl)oxy]-14β,15β:21,23-diepoxy-11β-hydroxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one is a complex, high-purity steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of specialized active pharmaceutical ingredients (APIs).
Application
- Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroidal drugs and bioactive molecules.
- Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing to ensure batch consistency.
- Biochemical Research: Serves as a tool compound in preclinical studies to investigate steroid hormone receptor interactions and signaling pathways.
- Process Chemistry Development: Employed in optimizing synthetic routes for scale-up and commercial production of target APIs.
- Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and medicinal chemistry.
- Custom Synthesis Starting Material: Provides a sophisticated core structure for the custom synthesis of proprietary compounds for client-specific R&D programs.
Basic Information
| Item | Details |
|---|---|
| Product Name | (13α,17S)-12α-[(2-Acetoxy-3-methyl-1-oxopentyl)oxy]-14β,15β:21,23-diepoxy-11β-hydroxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one |
| CAS No. | 11052-28-1 |
| Molecular Formula | C38H52O12 |
| Molecular Weight | 700.82 g/mol |
| Synonyms | 12α-[(2-Acetoxy-3-methyl-1-oxopentyl)oxy]-14β,15β:21,23-diepoxy-11β-hydroxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one; 12α-(2-Acetoxy-3-methyl-1-oxopentyloxy)-14β,15β:21,23-diepoxy-11β-hydroxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one; 24-Nor-5α-chola-1,20,22-triene-3-one, 12-[(2-acetoxy-3-methyl-1-oxopentyl)oxy]-14,15:21,23-diepoxy-11-hydroxy-7-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-, (7α,11β,12α,13α,14β,15β,17S)-; CAS 11052-28-1 |
| EINECS | Contact for details |
Quality Control
Our (13α,17S)-12α-[(2-Acetoxy-3-methyl-1-oxopentyl)oxy]-14β,15β:21,23-diepoxy-11β-hydroxy-7α-(2-hydroxy-3-methyl-1-oxobutoxy)-4,4,8-trimethyl-24-nor-5α-chola-1,20,22-trien-3-one is produced under strict quality management systems to ensure the highest standards of purity and consistency required for research and development. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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