Description

[2-(2-Fluoro-Phenyl)-Pyrimidin-5-Yl]-Methanol is a high-purity fluorinated pyrimidine derivative, a key synthetic intermediate valued for its unique molecular scaffold. This compound is essential for research and development in advanced pharmaceutical chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the pyrimidine core for bioactivity.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes and tool compounds to study biological pathways.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific electronic or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	[2-(2-Fluoro-Phenyl)-Pyrimidin-5-Yl]-Methanol
CAS No.	960198-67-8
Molecular Formula	C11H9FN2O
Molecular Weight	204.20 g/mol
Synonyms	(2-(2-Fluorophenyl)pyrimidin-5-yl)methanol; 5-(Hydroxymethyl)-2-(2-fluorophenyl)pyrimidine; 2-(2-Fluorophenyl)-5-pyrimidinemethanol; 2-(2-Fluorophenyl)pyrimidine-5-methanol; [2-(2-Fluorophenyl)pyrimidin-5-yl]methanol
EINECS	Contact for details

Quality Control

Every batch of [2-(2-Fluoro-Phenyl)-Pyrimidin-5-Yl]-Methanol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.