Description

Bromopentafluorobenzene is a highly fluorinated aromatic building block of significant importance in advanced chemical synthesis. Its unique structure, featuring a reactive bromine atom on a perfluorinated benzene ring, makes it a versatile precursor for introducing pentafluorophenyl groups into complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where it is used to create compounds with enhanced stability, bioavailability, and specific electronic properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs which often exhibit improved metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, where the pentafluorophenyl moiety can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for cross-coupling reactions, such as Suzuki-Miyaura couplings.
• Materials Science: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials, contributing to thermal stability and unique optoelectronic properties.
• Derivatization Agent: Used in analytical chemistry as a derivatization reagent for gas chromatography (GC) or mass spectrometry (MS) to improve the detection of certain analytes.
• Chemical Research: A fundamental reagent in organic synthesis laboratories for exploring new fluorination methodologies and constructing complex aromatic systems.

Basic Information

Product Name	Bromopentafluorobenzene
CAS No.	344-04-7
Molecular Formula	C6BrF5
Molecular Weight	246.96 g/mol
Synonyms	Pentafluorobromobenzene; 1-Bromo-2,3,4,5,6-pentafluorobenzene; Bromoperfluorobenzene; Perfluorobromobenzene; Benzene, bromopentafluoro-; NSC 9235; BFB
EINECS	206-447-9

Quality Control

Our Bromopentafluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reactive metals. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept upright and securely sealed to prevent moisture ingress and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density at 20°C	~1.95 g/mL
Boiling Point	~142-143 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.