Description

4,4,4-Trifluoro-3-Oxo-2-(Phenylhydrazono)Butyric Acid Ethyl Ester is a specialized fluorinated organic building block with a unique trifluoromethyl ketone hydrazone structure. This compound is valued for its role as a key intermediate in the synthesis of complex heterocycles and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated heterocyclic compounds and potential drug candidates, leveraging the biological activity imparted by the trifluoromethyl group.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atoms can improve metabolic stability and bioavailability.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex molecules via reactions such as cyclizations and condensations in medicinal chemistry.
• Material Science: Investigated for the preparation of specialized fluorinated polymers or dyes with unique optical or electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development and exploring new reaction pathways involving fluorinated substrates.

Basic Information

Product Name	4,4,4-Trifluoro-3-Oxo-2-(Phenylhydrazono)Butyric Acid Ethyl Ester
CAS No.	1494-98-0
Molecular Formula	C12H11F3N2O3
Molecular Weight	288.22 g/mol
Synonyms	Ethyl 4,4,4-Trifluoro-3-oxo-2-(phenylhydrazono)butanoate; Ethyl 2-(2-Phenylhydrazono)-4,4,4-trifluoro-3-oxobutanoate; 4,4,4-Trifluoro-3-oxo-2-(phenylhydrazono)butyric Acid Ethyl Ester; 2-(Phenylhydrazono)-4,4,4-trifluoroacetoacetic Acid Ethyl Ester; TFPHB Ethyl Ester; Butanoic acid, 4,4,4-trifluoro-3-oxo-2-(2-phenylhydrazono)-, ethyl ester; Ethyl (2Z)-4,4,4-trifluoro-3-oxo-2-(2-phenylhydrazinylidene)butanoate
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-3-Oxo-2-(Phenylhydrazono)Butyric Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.