Description

Pyrimidine, 4-Amino-2-(Fluoromethyl)-6-Methoxy- (8Ci) is a specialized fluorinated pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a reactive amino group with a fluoromethyl substituent, enabling precise modifications in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly in medicinal chemistry programs targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially for antiviral, anticancer, and CNS-targeted therapies.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the fluorinated pyrimidine core enhances biological activity and metabolic stability.
• Chemical Biology & Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or functional component in the design of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in universities and CROs for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	Pyrimidine, 4-Amino-2-(Fluoromethyl)-6-Methoxy- (8Ci)
CAS No.	16097-53-3
Molecular Formula	C6H8FN3O
Molecular Weight	157.15 g/mol
Synonyms	4-Amino-2-(fluoromethyl)-6-methoxypyrimidine; 2-(Fluoromethyl)-4-amino-6-methoxypyrimidine; 6-Methoxy-4-amino-2-fluoromethylpyrimidine; 4-Amino-6-methoxy-2-(fluoromethyl)pyrimidine; 16097-53-3; AI3-52066; SCHEMBL218424; CTK8G7221; ZINC000004079768; AKOS040759393; AS-57833; SY009540; STL283910
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-Amino-2-(Fluoromethyl)-6-Methoxy- (8Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.