Description

5-(Trifluoromethyl)-1H-1,2,3-Benzotriazole is a versatile heterocyclic compound featuring a benzotriazole core substituted with a trifluoromethyl group, offering unique electronic and steric properties. This compound is valued for its role as a key synthetic intermediate and functional additive in advanced material science and pharmaceutical chemistry. It is primarily sought by researchers and manufacturers in the agrochemical, pharmaceutical, and specialty polymer industries for developing novel active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Corrosion Inhibitor Precursor: Acts as a starting material for synthesizing high-performance corrosion inhibitors used in cooling water systems, metalworking fluids, and coatings.
• Polymer Additive: Incorporated into specialty polymers and resins to improve UV stability, thermal resistance, and chemical inertness.
• Ligand in Catalysis: Utilized in the preparation of nitrogen-donor ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Organic Electronic Materials: Investigated as a component in the development of organic light-emitting diodes (OLEDs) and semiconductors due to its electron-withdrawing characteristics.

Basic Information

Item	Details
Product Name	5-(Trifluoromethyl)-1H-1,2,3-Benzotriazole
CAS No.	1548-67-0
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	5-(Trifluoromethyl)benzotriazole; 5-Trifluoromethyl-1H-benzotriazole; 1H-Benzotriazole, 5-(trifluoromethyl)-; 5-Trifluoromethylbenzotriazole; 5-CF3-Benzotriazole; 5-Trifluoromethyl-1H-1,2,3-benzotriazole; α,α,α-Trifluoro-m-toluazimid; 5-(Trifluoromethyl)-1H-benzo[d][1,2,3]triazole
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1H-1,2,3-Benzotriazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.