Description

4,4′-Dithiobis-2-(Trifluoracetyl)Aminobutansure is a specialized organosulfur compound featuring a disulfide bridge and trifluoroacetyl-protected amine groups. This unique structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, peptide synthesis, and the development of high-performance polymers. Its controlled reactivity profile offers precise pathways for constructing novel chemical architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting sulfur-mediated biological pathways.
• Peptide Chemistry & Bioconjugation: Used for introducing disulfide linkages or as a protected amine precursor in peptide synthesis and protein modification.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or chemical resistance.
• Agrochemical Synthesis: Intermediate for creating advanced crop protection agents with specific activity profiles.
• Ligand & Catalyst Development: Precursor for synthesizing chelating ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme activity or cellular processes involving thiol-disulfide exchange.

Basic Information

Product Name	4,4′-Dithiobis-2-(Trifluoracetyl)Aminobutansure
CAS No.	105996-54-1
Molecular Formula	C12H14F6N2O4S2
Molecular Weight	428.37 g/mol
Synonyms	4,4'-Dithiobis[2-(trifluoroacetamido)butanoic acid]; 2,2'-Disulfanediylbis[4-(2,2,2-trifluoroacetamido)butanoic acid]; 4,4'-Dithiobis(2-trifluoroacetamidobutanoic acid); Bis(2-(trifluoroacetamido)-4-carboxybutyl) disulfide; 4,4'-Dithiobis(2-(trifluoroacetylamino)butyric acid); TFAB Disulfide Derivative; N2,N2'-Bis(trifluoroacetyl)cystine derivative
EINECS	Contact for details

Quality Control

Our production of 4,4′-Dithiobis-2-(Trifluoracetyl)Aminobutansure adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established specifications using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We operate under a quality management system aligned with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.