Description

n-Fluoro-o-Benzenedisulfonimide is a specialized fluorinating reagent and a key synthetic intermediate in advanced organic chemistry. Its value lies in its ability to act as a stable, shelf-stable source of electrophilic fluorine for the selective introduction of fluorine atoms into complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where the incorporation of fluorine is critical for modulating the biological activity, metabolic stability, and physical properties of target compounds.

Application

• As a versatile electrophilic fluorinating agent in the synthesis of fluorinated pharmaceuticals and bioactive molecules.
• Key intermediate for the preparation of N-fluorinated sulfonimides and other fluoroorganic compounds.
• Used in asymmetric synthesis and catalysis research for creating chiral, fluorinated building blocks.
• Employed in the development of advanced materials, including liquid crystals and polymers with tailored properties.
• Facilitates radiofluorination precursor chemistry for Positron Emission Tomography (PET) tracer development.
• Research reagent for studying fluorination mechanisms and developing new fluorination methodologies.

Basic Information

Product Name	n-Fluoro-o-Benzenedisulfonimide
CAS No.	1344-80-5
Molecular Formula	C6H4FNO4S2
Molecular Weight	237.23 g/mol
Synonyms	N-Fluoro-1,2-benzenedisulfonimide; N-Fluorobenzenesulfonimide; 1-Fluoro-1,2-benzenedisulfonimide; N-Fluoro-o-benzenedisulfonimide; NFSI; FBS; N-Fluorobis(phenylsulfonyl)imide; N-Fluorobenzenesulfonamide, N-(phenylsulfonyl) derivative
EINECS	Contact for details

Quality Control

Our n-Fluoro-o-Benzenedisulfonimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.