Description

2-Fluoro-2-Isobutylmalonamide is a specialized fluorinated malonamide derivative, a key building block in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine and the reactive malonamide moiety, enabling precise molecular modifications to enhance the properties of target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where the fluorine atom can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging fluorine's ability to increase lipophilicity and biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of compound libraries.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced polymers and coordination complexes.

Basic Information

Product Name	2-Fluoro-2-Isobutylmalonamide
CAS No.	18283-33-5
Molecular Formula	C7H13FN2O2
Molecular Weight	176.19 g/mol
Synonyms	2-Fluoro-2-(2-methylpropyl)propanediamide; 2-Fluoro-2-isobutylmalonic Acid Diamide; 2-Fluoro-2-isobutylmalonamide; 2-Fluoro-2-(2-methylpropyl)malonamide; Propanediamide, 2-fluoro-2-(2-methylpropyl)-; 18283-33-5; 2-Fluoro-2-isobutyl-malonamide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-2-Isobutylmalonamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.