Description

3,4-Bis(Trifluoromethyl)-1H-Pyrazole is a high-value fluorinated heterocyclic building block essential for advanced chemical synthesis. This compound matters for its unique structure, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as by material scientists working on specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups improve biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized N-heterocyclic carbene (NHC) ligands and other catalysts used in organometallic chemistry and cross-coupling reactions.
• Material Science: Incorporated into the backbone of specialty polymers and organic electronic materials to modify thermal stability, solubility, and electronic properties.
• Chemical Research: Employed in academic and industrial R&D for exploring new fluorination methodologies and constructing complex molecular architectures.

Basic Information

Product Name	3,4-Bis(Trifluoromethyl)-1H-Pyrazole
CAS No.	19968-19-5
Molecular Formula	C5H2F6N2
Molecular Weight	204.08 g/mol
Synonyms	3,4-Bis(trifluoromethyl)pyrazole; 1H-Pyrazole, 3,4-bis(trifluoromethyl)-; 3,4-Bis(trifluoromethyl)-1H-pyrazole; 3,4-Di(trifluoromethyl)pyrazole; 3,4-Bis(trifluoromethyl)pyrazole; 19968-19-5; 3,4-Bistrifluoromethylpyrazole; 3,4-Bis(trifluoromethyl)pyrazole (9CI)
EINECS	Contact for details

Quality Control

Our 3,4-Bis(Trifluoromethyl)-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.