Description

Benzonitrile, 4-(2-Bromo-1,1,2,2-Tetrafluoroethoxy)- is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a benzonitrile core with a bromo-tetrafluoroethoxy side chain, which provides distinct electronic and steric properties for constructing complex molecules. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• As a key pharmaceutical intermediate in the synthesis of novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• As a versatile building block in agrochemical research for creating new pesticides and herbicides with improved efficacy and environmental profiles.
• In material science for the development of specialty polymers, liquid crystals, or organic electronic materials that benefit from its specific fluorinated aromatic structure.
• As a precursor for ligand synthesis in catalysis, where the nitrile and halogenated ether groups can be further functionalized.
• For use in academic and industrial R&D exploring structure-activity relationships (SAR) in medicinal chemistry programs.
• In the synthesis of custom fluorinated fine chemicals and reference standards for analytical purposes.

Basic Information

Product Name	Benzonitrile, 4-(2-Bromo-1,1,2,2-Tetrafluoroethoxy)-
CAS No.	957372-61-1
Molecular Formula	C9H4BrF4NO
Molecular Weight	298.04 g/mol
Synonyms	4-(2-Bromo-1,1,2,2-tetrafluoroethoxy)benzonitrile; 1-Bromo-2,2,2-trifluoro-1-(trifluoromethoxy)ethylbenzene-4-carbonitrile; p-(2-Bromo-1,1,2,2-tetrafluoroethoxy)benzonitrile; 4-[(2-Bromo-1,1,2,2-tetrafluoroethoxy)]benzonitrile; Benzonitrile, p-(2-bromo-1,1,2,2-tetrafluoroethoxy)-; 957372-61-1
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 4-(2-Bromo-1,1,2,2-Tetrafluoroethoxy)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.