Description

4-[[(1R,2S)-2-Cyanocyclohexyl]Oxy]-2-(Trifluoromethyl)-Benzonitrie is a high-purity, advanced pharmaceutical intermediate featuring a chiral cyclohexyl backbone and a trifluoromethyl group, which are critical for imparting metabolic stability and bioavailability to target molecules. This compound is essential for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science: Investigated as a monomer or additive for developing specialty polymers with unique optical or electronic properties.
• Academic & Industrial R&D: Employed in methodological studies and scale-up process development for complex organic syntheses.

Basic Information

Product Name	4-[[(1R,2S)-2-Cyanocyclohexyl]Oxy]-2-(Trifluoromethyl)-Benzonitrie
CAS No.	956004-50-5
Molecular Formula	C15H13F3N2O
Molecular Weight	294.27 g/mol
Synonyms	2-(Trifluoromethyl)-4-[[(1R,2S)-2-cyanocyclohexyl]oxy]benzonitrile; (1R,2S)-2-(4-Cyano-3-(trifluoromethyl)phenoxy)cyclohexanecarbonitrile; 4-[(1R,2S)-2-Cyanocyclohexoxy]-2-(trifluoromethyl)benzonitrile; 956004-50-5; 4-((1R,2S)-2-cyanocyclohexyl)oxy)-2-(trifluoromethyl)benzonitrile
EINECS	Contact for details

Quality Control

Our production of 4-[[(1R,2S)-2-Cyanocyclohexyl]Oxy]-2-(Trifluoromethyl)-Benzonitrie adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, potency, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.