Description

Toreforant CAS NO 952494-46-1 is a high-purity, small molecule pharmaceutical intermediate and research chemical. This compound is of significant value for its role in the development and synthesis of novel therapeutic agents, particularly in the field of central nervous system (CNS) research. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in advanced drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used as a reference standard or a precursor in preclinical studies for neurological and psychiatric disorders.
• Chemical Synthesis: Serves as a versatile synthon in medicinal chemistry for creating novel compound libraries.
• Biochemical Research: Employed in vitro studies to investigate specific biological pathways and receptor interactions.
• Process Development: Utilized for scaling up and optimizing synthetic routes in pilot plant and manufacturing settings.

Basic Information

Product Name	Toreforant
CAS No.	952494-46-1
Molecular Formula	C23H24N4O3S
Molecular Weight	436.53 g/mol
Synonyms	N-(4-Fluoro-3-(trifluoromethyl)phenyl)-2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1,3-thiazole-4-carboxamide; Toreforant; ACT-129968; Setipiprant (Note: Setipiprant is a closely related compound, often referenced in searches); CRTh2 antagonist (class); DP2 receptor antagonist (class); 4-Thiazolecarboxamide derivative.
EINECS	Contact for details

Quality Control

Our Toreforant is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.