Description

Antazoline Phosphate is a white to off-white crystalline powder belonging to the class of antihistamines. This compound is a critical active pharmaceutical ingredient (API) valued for its potent H1-receptor antagonist properties. It is primarily required by pharmaceutical manufacturers for the formulation of ophthalmic solutions and nasal sprays used to treat allergic conjunctivitis and rhinitis. Our high-purity grade ensures reliable performance and consistency in final drug products.

Application

• Primary Active Pharmaceutical Ingredient (API) in ophthalmic solutions for allergic conjunctivitis.
• Key component in nasal spray formulations for the relief of allergic rhinitis symptoms.
• Intermediate in the synthesis of more complex antihistamine derivatives.
• Reference standard in analytical laboratories for quality control and method development.
• Used in clinical research and development of new anti-allergy medications.
• Component in veterinary pharmaceutical preparations for allergic conditions in animals.

Basic Information

Product Name	Antazoline Phosphate
CAS No.	154-68-7
Molecular Formula	C17H19N3·H3PO4
Molecular Weight	363.34 g/mol
Synonyms	Antazoline Phosphate; 2-[(N-Benzylanilino)methyl]-2-imidazoline phosphate; Antasten; Antazoline Dihydrogen Phosphate; Phenazoline; Antistin; Imidamin; Azalone; N-(Benzylanilino)methyl-2-imidazoline phosphate
EINECS	205-830-7

Quality Control

Our Antazoline Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications. We can support development projects with material meeting pharmaceutical grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.