Description

Pheniramine Maleate is a high-purity active pharmaceutical ingredient (API) belonging to the alkylamine class of antihistamines. It is a critical component in the formulation of effective allergy and cold medications, valued for its reliable antagonism of the H1 receptor. This compound is essential for manufacturers in the pharmaceutical industry producing oral and topical preparations for symptomatic relief. Our supply of Pheniramine Maleate CAS NO 132-20-7 is characterized by stringent quality control to meet the exacting standards of global drug production.

Application

Pheniramine Maleate serves as a versatile active ingredient with primary applications in human and veterinary medicine. Its antihistaminic properties make it suitable for a range of therapeutic formulations.

• Pharmaceutical Antihistamines: Primary API in tablets, syrups, and capsules for treating allergic conditions such as hay fever, urticaria, and allergic conjunctivitis.
• Cold & Flu Medications: Key component in multi-symptom relief formulas, often combined with analgesics and decongestants.
• Topical Preparations: Used in creams, ointments, and eye drops for localized anti-allergic and anti-pruritic (anti-itch) effects.
• Veterinary Pharmaceuticals: Incorporated into medications for managing allergic reactions and motion sickness in animals.
• Research & Development: Serves as a reference standard and building block in pharmacological research and new drug development.

Basic Information

Product Name	Pheniramine Maleate
CAS No.	132-20-7
Molecular Formula	C20H24N2O4
Molecular Weight	356.42 g/mol
Synonyms	Pheniramine hydrogen maleate; Prophenpyridamine maleate; Avil; Trimeton; Inhiston; 1-Phenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate; N-(4-Methylphenyl)-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine (Z)-2-butenedioate; FENIRAMINA MALEATO
EINECS	205-048-8

Quality Control

Our Pheniramine Maleate is manufactured under strict quality management systems. Each batch is tested to ensure it meets or exceeds relevant pharmacopoeial standards, including USP, EP, and BP monographs. Our comprehensive quality control protocol includes identity confirmation, purity assay, and stringent limits for related substances and residual solvents. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials and sources of heat or ignition. The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.