Description

Chloropheniramine is a potent, first-generation alkylamine antihistamine widely recognized for its efficacy in blocking H1 receptors. Its primary value lies in providing reliable relief from allergic symptoms, making it a cornerstone active pharmaceutical ingredient (API) in numerous therapeutic formulations. This compound is essential for manufacturers in the global pharmaceutical industry developing products for allergy, cold, and motion sickness relief.

Application

• Primary Active Pharmaceutical Ingredient (API) in antihistamine tablets and capsules.
• Key component in multi-symptom cold and flu relief medications.
• Formulation of sustained-release and extended-release oral dosage forms.
• Manufacturing of anti-allergy syrups and pediatric liquid formulations.
• Use in veterinary pharmaceuticals for allergic conditions in animals.
• Intermediate in the synthesis of more complex antihistamine derivatives.
• Research and development of novel drug delivery systems.

Basic Information

Product Name	Chloropheniramine
CAS No.	132-22-9
Molecular Formula	C16H19ClN2
Molecular Weight	274.79 g/mol
Synonyms	Chlorpheniramine; Chlorphenamine; 1-(4-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane; Piriton; Aller-Chlor; Chlortrimeton; Teldrin; Histafen; Phenetron; Chlor-Pro; Chlor-Tripolon
EINECS	205-056-6

Quality Control

Our Chloropheniramine is produced under strict quality management systems, with specifications designed to meet or exceed major pharmacopoeial standards such as USP, EP, and BP. Every batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 0.5%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Related Substances (HPLC)	Total impurities NMT 1.0% Any individual impurity NMT 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.