Description

Promethazine Teoclate is a high-purity pharmaceutical intermediate and active ingredient, specifically the teoclate salt form of the well-known antihistamine promethazine. This compound is critical for ensuring the stability, bioavailability, and precise formulation of final pharmaceutical products. It is primarily required by manufacturers in the pharmaceutical and life sciences sectors for the development and production of antiemetic and sedative medications.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of anti-nausea and motion sickness medications.
• Key Intermediate in the synthesis of advanced promethazine-based therapeutic agents.
• Research & Development material for pharmacological studies and new drug development.
• Reference Standard in analytical laboratories for quality control and method validation.
• Sedative Formulations used in certain medical procedures and treatments.
• Veterinary Pharmaceutical applications for animal health products.

Basic Information

Product Name	Promethazine Teoclate
CAS No.	17693-51-5
Molecular Formula	C17H20N2S • C7H7ClO2S
Molecular Weight	499.06 g/mol
Synonyms	Promethazine Teoclate; Promethazine 8-Chlorotheophyllinate; Promethazine Theoclate; 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, compd. with 8-chloro-1,3-dimethyl-2,6(1H,3H)-purinedione (1:1); Promethazine chlorotheophyllinate; Promethazine 8-chlorotheophylline salt; NSC 113927; Avomine (brand name); Histantil (brand name)
EINECS	Contact for details

Quality Control

Our Promethazine Teoclate CAS 17693-51-5 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.