Description

Chlorothen Hydrochloride is a high-purity pharmaceutical intermediate and active ingredient of significant commercial importance. Its primary value lies in its role as a key building block for the synthesis of antihistamines and other specialized therapeutic agents. This compound is essential for manufacturers and R&D facilities in the global pharmaceutical, fine chemical, and life science sectors seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of antihistamine drugs and other active pharmaceutical ingredients (APIs).
• Active Pharmaceutical Ingredient (API): Used directly in the formulation of specific therapeutic preparations.
• Biochemical Research: Serves as a reagent and standard in pharmacological and biochemical studies, particularly related to histamine receptors.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex organic molecules in research and development.
• Reference Standard: Used in analytical laboratories for quality control and method development via HPLC, GC, or other techniques.

Basic Information

Product Name	Chlorothen Hydrochloride
CAS No.	135-35-3
Molecular Formula	C14H19ClN2S • HCl
Molecular Weight	319.29 g/mol
Synonyms	Chloropyrilamine Hydrochloride; Chlorothen Citrate (related salt); N,N-Dimethyl-N'-(2-pyridyl)-N'-(5-chloro-2-thenyl)ethylenediamine Hydrochloride; Histachlorazine Hydrochloride; 1-(5-Chloro-2-thenyl)-2-(dimethylaminoethylamino)pyridine Hydrochloride; Chlorpheniramine analogue; C14H19ClN2S • HCl
EINECS	205-192-6

Quality Control

Our Chlorothen Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) documenting purity (typically ≥98% by HPLC), residual solvents, and related substances is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.