Description

Methapyrilene Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its specific pharmacological activity and serves as a critical building block in the development and synthesis of specialized therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in medicinal chemistry and analytical studies.

Application

• Pharmaceutical Intermediate: Key starting material or precursor in the synthesis of active pharmaceutical ingredients (APIs) with antihistaminic properties.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing.
• Biochemical Research: Employed in pharmacological and toxicological studies to investigate histamine receptor interactions and metabolic pathways.
• Impurity Standard: Serves as a known impurity standard in the HPLC analysis of related pharmaceutical compounds to ensure product purity and safety.
• Chemical Synthesis: A versatile building block for organic chemists in the development of novel chemical entities and structural analogs.

Basic Information

Product Name	Methapyrilene Hydrochloride
CAS No.	135-23-9
Molecular Formula	C14H19N3S·HCl
Molecular Weight	297.85 g/mol
Synonyms	Methapyrilene HCl; N,N-Dimethyl-N'-(2-pyridyl)-N'-(2-thienylmethyl)ethylenediamine hydrochloride; Thenylpyramine hydrochloride; Histadyl; Semikon; Thenylene; 1,2-Ethanediamine, N,N-dimethyl-N'-2-pyridinyl-N'-2-thienylmethyl-, monohydrochloride
EINECS	205-183-3

Quality Control

Our Methapyrilene Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, IR, and other relevant pharmacopeial tests. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical development and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.