Description

Cyproheptadine is a first-generation piperidine antihistamine and serotonin antagonist. This versatile active pharmaceutical ingredient (API) is valued for its potent dual mechanism of action, providing reliable therapeutic effects. It is primarily required by pharmaceutical manufacturers for the formulation of prescription medications targeting allergic conditions and appetite stimulation. Global B2B buyers source Cyproheptadine CAS NO 129-03-3 for its established efficacy in clinical applications.

Application

Cyproheptadine serves as a critical component in various pharmaceutical and research applications due to its pharmacological profile.

• Pharmaceutical API: Primary use in the manufacture of prescription antihistamine tablets and syrups for allergic rhinitis, conjunctivitis, and chronic urticaria.
• Appetite Stimulant: Formulated into medications to promote weight gain and address appetite loss in clinical settings.
• Serotonin Antagonist: Used in research and potential therapeutic areas related to serotonin syndrome and migraine prophylaxis.
• Veterinary Medicine: Applicable in veterinary pharmaceuticals for allergic and dermatological conditions in animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control laboratories and regulatory testing.
• Clinical Research: Utilized in preclinical and clinical studies investigating antihistamine and antiserotonergic agents.

Basic Information

Product Name	Cyproheptadine
CAS No.	129-03-3
Molecular Formula	C21H21N
Molecular Weight	287.40 g/mol
Synonyms	Periacin; Periactin; Nuran; Cyproheptadine Hydrochloride (salt form); 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine; MK-141; Deseril; Vimicon; Cipractin; Cinazyn
EINECS	204-924-3

Quality Control

Our Cyproheptadine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identification, assay, and impurity profile checks. Certificates of Analysis (COA) documenting compliance with in-house specifications are available upon request. We support customers requiring alignment with USP, EP, or other pharmacopeial monographs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.