Description

2-[4-(Trifluoromethoxy)Phenoxy]Acetonitrile is a high-value, fluorinated aromatic nitrile building block, distinguished by its trifluoromethoxy and phenoxy substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry and crop protection product synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Serves as a versatile precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethoxy group.
• Liquid Crystal & OLED Materials: Used in the research and production of specialty chemicals for electronic displays and organic light-emitting diodes due to its aromatic and fluorinated structure.
• Polymer Science: Acts as a monomer or modifier in the synthesis of high-performance, specialty polymers with enhanced chemical resistance and thermal stability.
• Chemical Research & Development: Employed as a standard or building block in organic synthesis for creating complex fluorinated compounds in academic and industrial labs.

Basic Information

Product Name	2-[4-(Trifluoromethoxy)Phenoxy]Acetonitrile
CAS No.	952182-87-5
Molecular Formula	C9H6F3NO2
Molecular Weight	217.14 g/mol
Synonyms	4-(Trifluoromethoxy)phenoxyacetonitrile; 2-[4-(Trifluoromethoxy)phenoxy]ethanenitrile; α-((4-(Trifluoromethoxy)phenoxy)acetonitrile; p-Trifluoromethoxyphenoxyacetonitrile; 1-[4-(Trifluoromethoxy)phenoxy]acetonitrile; TFMPA; (4-Trifluoromethoxyphenoxy)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-[4-(Trifluoromethoxy)Phenoxy]Acetonitrile is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), identity (by IR and NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.