Description

4-Fluoro-1-Nitro-2-Vinylbenzene is a versatile fluorinated aromatic building block characterized by its reactive vinyl and nitro substituents. This compound is crucial for the synthesis of complex molecules, offering a handle for further functionalization through cross-coupling, cycloaddition, and reduction chemistries. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The vinyl group enables Heck, Suzuki, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Cycloaddition Substrate: Participates in Diels-Alder and other pericyclic reactions for constructing complex carbocyclic and heterocyclic systems.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Fluoro-1-Nitro-2-Vinylbenzene
CAS No.	951667-82-6
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	1-Fluoro-4-nitro-2-vinylbenzene; 2-Vinyl-4-fluoronitrobenzene; 4-Fluoro-2-vinylnitrobenzene; 4-Fluoro-1-nitro-2-ethenylbenzene; 2-Ethenyl-1-fluoro-4-nitrobenzene; 4-Fluoro-2-vinyl-1-nitrobenzene; (2-Fluoro-5-nitrophenyl)ethylene; Benzene, 1-fluoro-4-nitro-2-ethenyl-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1-Nitro-2-Vinylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.