Description

5-Chloro-2-Nitrobenzotrifluoride is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and nitro substituents make it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for R&D and production in the agrochemical and pharmaceutical industries, where it is used to develop active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Pharmaceutical Synthesis: Serves as a building block for active pharmaceutical ingredients (APIs), particularly in the development of compounds requiring halogen and nitro functional groups for further transformation.
• Dye and Pigment Manufacturing: Used in the production of specialized dyes and pigments, where the nitro and chloro groups contribute to color fastness and molecular stability.
• Liquid Crystal and Electronic Materials: Acts as an intermediate in the synthesis of advanced materials for liquid crystal displays (LCDs) and organic electronics.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	5-Chloro-2-Nitrobenzotrifluoride
CAS No.	118-83-2
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	2-Nitro-5-chlorobenzotrifluoride; 1-Chloro-4-nitro-2-(trifluoromethyl)benzene; 5-Chloro-α,α,α-trifluoro-2-nitrotoluene; 2-Nitro-α,α,α-trifluoro-5-chlorotoluene; 5-Chloro-2-nitrobenzylidene trifluoride; 2-Nitro-5-chlorobenzyl trifluoride; 5-Chloro-2-nitro-α,α,α-trifluorotoluene; 2-Chloro-5-nitrobenzotrifluoride (isomer)
EINECS	204-280-1

Quality Control

Our 5-Chloro-2-Nitrobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical and agrochemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.