Description

2,2-Difluoro-5-Nitro-1,3-Benzodioxole is a specialized fluorinated aromatic compound that serves as a valuable synthetic intermediate. Its unique structure, featuring both nitro and difluoromethylene-dioxole functional groups, makes it a key building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological mechanisms and enzyme activity.
• Organic Synthesis Building Block: Provides a versatile scaffold for palladium-catalyzed cross-coupling reactions, nucleophilic aromatic substitutions, and other transformations to create diverse chemical libraries.

Basic Information

Product Name	2,2-Difluoro-5-Nitro-1,3-Benzodioxole
CAS No.	1645-96-1
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	5-Nitro-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-5-nitrobenzo-1,3-dioxole; 1,3-Benzodioxole, 2,2-difluoro-5-nitro-; 1645-96-1; 5-Nitro-2,2-difluorobenzodioxole; Difluoronitrobenzodioxole
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-5-Nitro-1,3-Benzodioxole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.