Description

1-Nitro-3-(1,1,2,2-Tetrafluoroethoxy)Benzene is a specialized fluorinated aromatic nitro compound, serving as a valuable intermediate in advanced organic synthesis. Its unique structure, featuring both a nitro group and a tetrafluoroethoxy side chain, makes it a critical building block for introducing fluorine-containing motifs into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients with enhanced properties such as metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs) to modify dielectric anisotropy and viscosity.
• Organic Electronics: Intermediate in the production of fluorinated organic semiconductors and charge-transport materials.
• Advanced Polymer Modification: Imparts fluorine content into polymer backbones to enhance chemical resistance, thermal stability, and surface properties.
• Dye and Pigment Chemistry: Used in the synthesis of specialized fluorinated dyes with unique color fastness and solubility characteristics.

Basic Information

Product Name	1-Nitro-3-(1,1,2,2-Tetrafluoroethoxy)Benzene
CAS No.	1644-21-9
Molecular Formula	C8H5F4NO3
Molecular Weight	239.13 g/mol
Synonyms	3-(1,1,2,2-Tetrafluoroethoxy)nitrobenzene; 1-Nitro-3-(tetrafluoroethoxy)benzene; m-Nitro-(1,1,2,2-tetrafluoroethoxy)benzene; Benzene, 1-nitro-3-(1,1,2,2-tetrafluoroethoxy)-; 3-Nitrophenyl 1,1,2,2-tetrafluoroethyl ether; 1,1,2,2-Tetrafluoroethyl 3-nitrophenyl ether
EINECS	Contact for details

Quality Control

Our 1-Nitro-3-(1,1,2,2-Tetrafluoroethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP standards for pharmaceutical-grade intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.