Description

m-Xylene, 2-Fluoro-4-Nitro- (7Ci,8Ci) is a specialized fluorinated nitro aromatic compound, serving as a high-value synthetic intermediate. Its unique structure, featuring both a fluorine atom and a nitro group on a meta-xylene backbone, makes it a critical building block for introducing specific functionalities into target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and advanced materials sectors who require precise molecular architecture for creating novel active ingredients or functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic moieties for enhanced metabolic stability, bioavailability, or receptor binding affinity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine and nitro groups contribute to biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds, enabling fine-tuning of electronic properties, solubility, and mesophase behavior.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized nitro- and fluoro-substituted dyes and pigments, offering unique color fastness and spectral properties.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with specific thermal, chemical, or surface characteristics.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, particularly in cross-coupling reactions and nucleophilic aromatic substitution involving fluorinated arenes.

Basic Information

Product Name	m-Xylene, 2-Fluoro-4-Nitro- (7Ci,8Ci)
CAS No.	1736-84-1
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	2-Fluoro-4-nitrom-xylene; 1,3-Dimethyl-2-fluoro-4-nitrobenzene; 2-Fluoro-1,3-dimethyl-4-nitrobenzene; 4-Nitro-2-fluoro-1,3-dimethylbenzene; 2-Fluoro-4-nitro-m-xylene; 2-Fluoro-4-nitromethylbenzene (ambiguous); Benzene, 1,3-dimethyl-2-fluoro-4-nitro-; 2-Fluoro-4-nitro-1,3-xylene
EINECS	217-087-2

Quality Control

Our m-Xylene, 2-Fluoro-4-Nitro- (7Ci,8Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, GC for residual solvents, and spectroscopic methods (IR, NMR) for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The compound should be handled in accordance with good laboratory practices to prevent contamination and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.