Description

2-Methoxy-5-Nitrobenzotrifluoride is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both a nitro and a trifluoromethyl group, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments, leveraging the nitro group for color development.
• Organic Electronic Materials: A candidate intermediate for the development of materials used in organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.

Basic Information

Product Name	2-Methoxy-5-Nitrobenzotrifluoride
CAS No.	654-76-2
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	1-Methoxy-2-nitro-4-(trifluoromethyl)benzene; 2-Nitro-5-(trifluoromethyl)anisole; 4-(Trifluoromethyl)-2-nitroanisole; 5-Nitro-2-methoxybenzotrifluoride; α,α,α-Trifluoro-2-methoxy-5-nitrotoluene; 2-Methoxy-α,α,α-trifluoro-5-nitrotoluene; Benzene, 1-methoxy-2-nitro-4-(trifluoromethyl)-
EINECS	211-498-9

Quality Control

Our 2-Methoxy-5-Nitrobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.