Description

3-Fluoro-6-Nitro-o-Xylene is a high-purity, synthetically valuable fluorinated aromatic intermediate. This compound is essential for constructing complex molecular architectures, particularly in the development of advanced agrochemicals and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for its role in introducing both fluorine and nitro functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex, color-fast dyes and functional pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig amination, enabling rapid diversification.
• Fluorine Chemistry Studies: A standard reagent in academic and industrial laboratories for studying the effects of fluorine substitution on aromatic systems.

Basic Information

Item	Details
Product Name	3-Fluoro-6-Nitro-o-Xylene
CAS No.	1736-87-4
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	1,2-Dimethyl-3-fluoro-6-nitrobenzene; 3-Fluoro-6-nitro-1,2-dimethylbenzene; 2,3-Dimethyl-1-fluoro-4-nitrobenzene; 3-Fluoro-6-nitro-o-xylene; 3-Fluoro-6-nitro-ortho-xylene; 6-Nitro-3-fluoro-o-xylene; o-Xylene, 3-fluoro-6-nitro-; 3-Fluoro-6-nitro-1,2-xylene
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-6-Nitro-o-Xylene is produced under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.