Description

Pentafluoronitrosobenzene CAS NO 1423-13-8 is a highly fluorinated nitroso aromatic compound, serving as a versatile and reactive intermediate in advanced organic synthesis. Its unique structure, featuring a nitroso group attached to a perfluorinated benzene ring, makes it a critical building block for introducing fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise fluorination to modify compound properties such as metabolic stability, lipophilicity, and chemical reactivity.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates to enhance bioavailability and metabolic resistance.
• Agrochemical Synthesis: Serves as a key precursor in creating novel fluorinated pesticides, herbicides, and fungicides with improved efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Employed in the production of fluorinated components for liquid crystal displays (LCDs) and organic electronic materials.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to incorporate fluorinated groups into polymers, improving chemical resistance and surface properties.
• Organic Synthesis Reagent: Utilized in various name reactions, such as cycloadditions and radical reactions, as a source of the nitroso and pentafluorophenyl groups.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	Pentafluoronitrosobenzene
CAS No.	1423-13-8
Molecular Formula	C6F5NO
Molecular Weight	197.07 g/mol
Synonyms	Perfluoronitrosobenzene; Nitroso-pentafluorobenzene; Pentafluorophenylnitroso; 2,3,4,5,6-Pentafluoronitrosobenzene; NSC 88287; Nitrosobenzene, pentafluoro-; 1-Nitroso-2,3,4,5,6-pentafluorobenzene
EINECS	215-825-6

Quality Control

Our Pentafluoronitrosobenzene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging. Isolate from incompatible materials such as strong reducing agents and bases.

Specification

Item	Specification
Appearance	Green to blue-green crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	34 - 38 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.