Description

1-Fluoro-3-(2,2,2-Trifluoro-Ethoxy)-Propan-2-Ol is a specialized fluorinated organic compound, serving as a valuable building block in advanced chemical synthesis. Its unique structure, featuring both fluorine and a trifluoroethoxy group, makes it a critical intermediate for introducing specific physicochemical properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where fluorine incorporation improves efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric materials.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for fluorine-18 labeled radiopharmaceuticals for medical imaging.

Basic Information

Product Name	1-Fluoro-3-(2,2,2-Trifluoro-Ethoxy)-Propan-2-Ol
CAS No.	948294-32-4
Molecular Formula	C5H8F4O2
Molecular Weight	176.11 g/mol
Synonyms	2-Propanol, 1-fluoro-3-(2,2,2-trifluoroethoxy)-; 1-Fluoro-3-(2,2,2-trifluoroethoxy)propan-2-ol; 3-(2,2,2-Trifluoroethoxy)-1-fluoropropan-2-ol; 2-Hydroxy-3-(2,2,2-trifluoroethoxy)-1-fluoropropane; Glycidyl 2,2,2-trifluoroethyl ether, fluoro derivative; TFEO-FP
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-(2,2,2-Trifluoro-Ethoxy)-Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced R&D and scale-up processes. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.