Description

2-Fluoro-α-Methyltyrosine is a fluorinated derivative of the amino acid tyrosine, serving as a key synthetic intermediate and research chemical. Its value lies in the strategic introduction of fluorine, which can significantly alter the metabolic stability, bioavailability, and binding affinity of bioactive molecules. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutics, particularly in neurology and oncology, as well as in advanced PET (Positron Emission Tomography) tracer synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of fluorinated drug candidates targeting enzymes and receptors.
• PET Radiopharmaceutical Precursor: Used in research for developing fluorine-18 (18F) labeled tracers for diagnostic imaging.
• Biochemical Research: Tool compound for studying amino acid transport, metabolism, and enzyme inhibition mechanisms.
• Neurology Research: Investigated in models related to neurotransmitter synthesis and neurodegenerative diseases.
• Fine Chemical Synthesis: Employed in custom synthesis and the production of complex, high-value fluorinated organic molecules.
• Academic & Institutional Research: Used in universities and research institutes for chemical biology and medicinal chemistry projects.

Basic Information

Product Name	2-Fluoro-α-Methyltyrosine
CAS No.	16855-16-6
Molecular Formula	C10H12FNO3
Molecular Weight	213.21 g/mol
Synonyms	2-Fluoro-α-methyltyrosine; (2S)-2-Amino-3-(4-hydroxy-3-fluorophenyl)-2-methylpropanoic acid; L-2-Fluoro-α-methyltyrosine; α-Methyl-2-fluorotyrosine; 2-F-AMT; FMT; 2-Fluoro-α-methyl-L-tyrosine; 2-Fluoro-α-methyltyrosine (isomer unspecified)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-α-Methyltyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.