Description

2-Chloro-2-Fluoro-2-Phenylacetonitrile is a versatile fluorinated and chlorinated aromatic nitrile building block. This compound matters for its unique reactivity profile, offering chemists a bifunctional handle for constructing complex molecules in advanced synthetic pathways. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications such as the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and chlorine atoms can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis Reagent: Employed in various name reactions and coupling chemistries to introduce the phenylacetonitrile moiety with halogen functionalities.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new reaction methodologies and heterocyclic compound libraries.

Basic Information

Product Name	2-Chloro-2-Fluoro-2-Phenylacetonitrile
CAS No.	948014-31-1
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	α-Chloro-α-fluoro-α-phenylacetonitrile; 2-Fluoro-2-chloro-2-phenylacetonitrile; (Chlorofluorophenyl)acetonitrile; Phenyl(chlorofluoro)acetonitrile; 2-Chloro-2-fluoro-2-phenylethanenitrile; 948014-31-1; Benzeneacetonitrile, α-chloro-α-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-2-Fluoro-2-Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.