Description

3-Amino-4-Bromo-2,6-Difluorobenzonitrile is a high-value, multi-functional aromatic intermediate featuring a unique combination of reactive sites, including amino, bromo, fluoro, and cyano groups. This compound matters for its critical role in the synthesis of complex, biologically active molecules, enabling precise structural modifications and the introduction of key pharmacophores. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials and functional dyes.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast dyes and functional pigments.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	3-Amino-4-Bromo-2,6-Difluorobenzonitrile
CAS No.	946817-63-6
Molecular Formula	C7H3BrF2N2
Molecular Weight	233.01 g/mol
Synonyms	4-Bromo-2,6-difluoro-3-aminobenzonitrile; 2,6-Difluoro-3-amino-4-bromobenzonitrile; 3-Amino-4-bromo-2,6-difluorobenzene carbonitrile; Benzonitrile, 3-amino-4-bromo-2,6-difluoro-; 946817-63-6; 3-Amino-4-bromo-2,6-difluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Bromo-2,6-Difluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.