Description

4-[(3-Fluorophenyl)(Hydroxy)Methyl]Benzonitrile is a high-purity fluorinated benzonitrile derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its molecular structure, featuring both a fluorophenyl group and a benzonitrile moiety, makes it a versatile precursor for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is essential for research and production in pharmaceutical chemistry, agrochemical development, and materials science, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used as a building block for developing advanced pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the synthesis of advanced polymers and liquid crystals, where the fluorinated aromatic unit modifies material properties.
• Chemical Biology Probe Synthesis: Utilized in constructing molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-[(3-Fluorophenyl)(Hydroxy)Methyl]Benzonitrile
CAS No.	944648-35-5
Molecular Formula	C14H10FNO
Molecular Weight	227.24 g/mol
Synonyms	4-[(3-Fluorophenyl)(Hydroxy)Methyl]benzonitrile; (3-Fluorophenyl)(4-cyanophenyl)methanol; α-(3-Fluorophenyl)-4-cyanobenzyl alcohol; 4-[(Hydroxy)(3-fluorophenyl)methyl]benzonitrile; Benzonitrile, 4-[(3-fluorophenyl)hydroxymethyl]-; 4-Cyano-α-(3-fluorophenyl)benzyl alcohol; 4-(Hydroxy(3-fluorophenyl)methyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-[(3-Fluorophenyl)(Hydroxy)Methyl]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.