Description

2,3-Difluoro-4-Iodobenzonitrile is a high-value, multi-functional halogenated aromatic building block, distinguished by its unique combination of fluorine and iodine substituents. This compound is critical for introducing steric and electronic effects in advanced molecular architectures, enabling precise tuning of material and biological properties. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the difluoro and iodo groups enhance bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing polarizable, electron-deficient cores in advanced electronic materials for displays and lighting.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for cross-coupling catalysts, leveraging the iodine atom for metal complexation.
• Chemical Biology Probes: Utilized as a versatile handle for bioconjugation and the development of molecular probes for imaging and diagnostic applications.
• Polymer & Specialty Chemical Modifier: Incorporated into polymer backbones or as a terminal group to impart specific characteristics like hydrophobicity, thermal stability, or optical properties.

Basic Information

Item	Details
Product Name	2,3-Difluoro-4-Iodobenzonitrile
CAS No.	943830-91-9
Molecular Formula	C7H2F2IN
Molecular Weight	276.99 g/mol
Synonyms	4-Iodo-2,3-difluorobenzonitrile; 2,3-Difluoro-4-iodobenzonitrile; 2,3-Difluoro-4-iodo-benzonitrile; Benzonitrile, 2,3-difluoro-4-iodo-; 943830-91-9; 4-Cyano-2,3-difluoroiodobenzene; 2,3-Difluoro-4-iodophenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-Iodobenzonitrile is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.