Description

3-Bromo-6-Chloro-2-Fluorobenzonitrile is a high-purity, multi-halogenated benzonitrile derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystal materials.
• Chemical Biology: Employed as a molecular probe or labeling reagent due to its reactive nitrile and halogen functional groups.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination to create biaryl structures.

Basic Information

Product Name	3-Bromo-6-Chloro-2-Fluorobenzonitrile
CAS No.	943830-79-3
Molecular Formula	C7H2BrClFN
Molecular Weight	234.45 g/mol
Synonyms	2-Fluoro-3-bromo-6-chlorobenzonitrile; 6-Chloro-3-bromo-2-fluorobenzonitrile; Benzonitrile, 3-bromo-6-chloro-2-fluoro-; 3-Bromo-6-chloro-2-fluorobenzocarbonitrile; 943830-79-3; 2-Fluoro-6-chloro-3-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Chloro-2-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.