Description

2,4,6-Tribromo-3,5-Difluorobenzonitrile is a high-value, multi-halogenated aromatic nitrile building block. This compound matters for its unique molecular architecture, offering multiple reactive sites for selective functionalization in advanced synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromine and fluorine atoms contribute to potency and environmental persistence profiles.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials with unique electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the activated bromine atoms ortho and para to the electron-withdrawing nitrile group.
• Ligand and Catalyst Development: Useful for constructing sophisticated chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	2,4,6-Tribromo-3,5-Difluorobenzonitrile
CAS No.	943528-40-3
Molecular Formula	C7Br3F2N
Molecular Weight	395.79 g/mol
Synonyms	3,5-Difluoro-2,4,6-tribromobenzonitrile; 2,4,6-Tribromo-3,5-difluorobenzonitrile; Benzonitrile, 2,4,6-tribromo-3,5-difluoro-; Tribromodifluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2,4,6-Tribromo-3,5-Difluorobenzonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.