Description

tert-Butyl 2-Amino-1-(3-Fluorophenyl)Ethylcarbamate is a high-purity, fluorinated carbamate derivative serving as a critical chiral building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for introducing specific stereochemistry and functional groups. It is primarily utilized by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Peptidomimetic Chemistry: Used in the construction of modified peptide backbones to enhance metabolic stability and bioavailability.
• Agrochemical Development: Serves as a precursor in the research and production of novel fluorinated pesticides and herbicides.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Chemical Biology Probes: Useful for labeling and studying biological pathways due to its reactive amine group protected by a Boc (tert-butoxycarbonyl) group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	tert-Butyl 2-Amino-1-(3-Fluorophenyl)Ethylcarbamate
CAS No.	943325-32-4
Molecular Formula	C13H19FN2O2
Molecular Weight	254.30 g/mol
Synonyms	1-(3-Fluorophenyl)-2-[(tert-butoxycarbonyl)amino]ethanamine; 2-Amino-1-(3-fluorophenyl)ethyl carbamic acid tert-butyl ester; tert-Butyl N-[2-amino-1-(3-fluorophenyl)ethyl]carbamate; Boc-3-F-Phe-NH2; (R/S)-tert-Butyl 2-amino-1-(3-fluorophenyl)ethylcarbamate; 3-Fluoro-DL-phenylalanine tert-butyl carbamate; N-Boc-1-(3-fluorophenyl)-1,2-ethanediamine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Amino-1-(3-Fluorophenyl)Ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (where applicable), and spectroscopic identification (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Specify enantiomer (Contact for details)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.