Description

3-(3-Cyano-4-Fluorophenyl)-1-Propene is a specialized fluorinated aromatic nitrile building block with a reactive terminal alkene group. This unique molecular architecture makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and high-performance agrochemicals. It is essential for research and development chemists in the life sciences and fine chemical industries seeking to introduce fluorinated, cyano-functionalized aromatic systems into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic components in electronic display and lighting technologies.
• Polymer & Resin Modifier: Incorporated to introduce specific functional groups (cyano, fluoro) into polymer backbones, altering material properties like chemical resistance and dielectric constant.
• Cross-coupling Reactions: The alkene and aryl halide (via fluor displacement) functionalities make it a versatile substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorinated compounds and their properties.

Basic Information

Product Name	3-(3-Cyano-4-Fluorophenyl)-1-Propene
CAS No.	943247-49-2
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	4-Fluoro-3-(2-propen-1-yl)benzonitrile; 3-(4-Fluoro-3-cyanophenyl)prop-1-ene; 1-(2-Propenyl)-4-fluoro-3-cyanobenzene; 4-Fluoro-3-(prop-2-en-1-yl)benzonitrile; 3-Cyano-4-fluorophenylallyl; 3-Allyl-4-fluorobenzonitrile; (4-Fluoro-3-cyanophenyl)propene; 3-(3-Cyano-4-fluorophenyl)propene
EINECS	Contact for details

Quality Control

Our production of 3-(3-Cyano-4-Fluorophenyl)-1-Propene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and reliability for your synthetic processes. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.