Description

Benzonitrile, 2-Amino-5-Fluoro-3-Methyl- is a fluorinated aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and nitrile functional groups on a fluorinated benzene ring, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for diagnostic and bio-imaging applications.

Basic Information

Product Name	Benzonitrile, 2-Amino-5-Fluoro-3-Methyl-
CAS No.	939990-04-2
Molecular Formula	C8H7FN2
Molecular Weight	150.15 g/mol
Synonyms	2-Amino-5-fluoro-3-methylbenzonitrile; 3-Methyl-5-fluoro-2-aminobenzonitrile; 5-Fluoro-2-amino-3-methylbenzonitrile; 2-Cyano-6-fluoro-4-methylaniline; 4-Methyl-2-amino-6-fluorobenzonitrile; 2-Amino-6-fluoro-4-methylbenzonitrile; 939990-04-2; AFMB
EINECS	Contact for details

Quality Control

Our production of 2-Amino-5-Fluoro-3-Methylbenzonitrile adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.