Description

(2-Fluoro-4-Nitrophenyl)Methanamine is a specialized aromatic amine building block featuring both a fluorine substituent and a nitro group on the phenyl ring. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand design, and the creation of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting specific biological pathways where fluorine substitution is critical for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the nitro and amine groups for further chemical transformations.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, dyes, and photoactive materials where its electronic properties can be fine-tuned.
• Chemical Biology Probes: Useful for constructing fluorescent tags or affinity probes for studying biological systems.
• Academic & Industrial R&D: A versatile reagent for exploratory synthetic chemistry in both university laboratories and corporate research centers.

Basic Information

Product Name	(2-Fluoro-4-Nitrophenyl)Methanamine
CAS No.	937783-91-0
Molecular Formula	C7H7FN2O2
Molecular Weight	170.14 g/mol
Synonyms	1-(2-Fluoro-4-nitrophenyl)methanamine; (2-Fluoro-4-nitrobenzyl)amine; 2-Fluoro-4-nitrobenzylamine; 1-(Aminomethyl)-2-fluoro-4-nitrobenzene; α-Amino-2-fluoro-4-nitrotoluene; 2-Fluoro-4-nitrobenzenemethanamine; 4-Nitro-2-fluorobenzylamine
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-Nitrophenyl)Methanamine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding R&D and scale-up processes. We adhere to cGMP principles where applicable, and our quality systems support compliance with global regulatory standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.