Description

3-[(2,4-Difluorophenyl)Methyl]Azetidine CAS NO 937625-45-1 is a high-value, fluorinated azetidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique structural features, combining a constrained azetidine ring with a difluorinated aromatic moiety, which are highly sought after for modulating the physicochemical and pharmacokinetic properties of target molecules. Pharmaceutical and agrochemical R&D teams need this intermediate for developing novel active ingredients, particularly in the areas of medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in creating advanced fungicides, herbicides, and insecticides where the difluorophenyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and target engagement.

Basic Information

Product Name	3-[(2,4-Difluorophenyl)Methyl]Azetidine
CAS No.	937625-45-1
Molecular Formula	C10H11F2N
Molecular Weight	183.20 g/mol
Synonyms	1-(2,4-Difluorobenzyl)azetidine; 3-[(2,4-Difluorophenyl)methyl]azetidine; Azetidine, 3-[(2,4-difluorophenyl)methyl]-; 2,4-Difluorobenzylazetidine; 1-(2,4-Difluorobenzyl)azacyclobutane; (2,4-Difluorophenyl)methylazetidine; 937625-45-1; 3-(2,4-Difluorobenzyl)azetidine
EINECS	Contact for details

Quality Control

Our 3-[(2,4-Difluorophenyl)Methyl]Azetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.