Description

n-(3,5-Bis(Trifluoromethyl)Phenyl)-2-Chloropropanamide is a high-value, halogenated aromatic amide building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a reactive 2-chloropropanamide group and electron-deficient trifluoromethyl-substituted phenyl ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting protease inhibitors or other biologically active scaffolds.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, or insecticides, leveraging the bioactivity often associated with the trifluoromethylphenyl moiety.
• Material Science Research: Used in the synthesis of specialty polymers or advanced organic materials where the introduction of fluorine atoms can alter physical properties like solubility or thermal stability.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke intermediates for client projects.

Basic Information

Product Name	n-(3,5-Bis(Trifluoromethyl)Phenyl)-2-Chloropropanamide
CAS No.	937604-58-5
Molecular Formula	C11H6ClF6NO
Molecular Weight	317.61 g/mol
Synonyms	2-Chloro-N-[3,5-bis(trifluoromethyl)phenyl]propanamide; 2-Chloro-N-(3,5-bis(trifluoromethyl)phenyl)propanamide; α-Chloropropion-3,5-bis(trifluoromethyl)anilide; N-(3,5-Bis(trifluoromethyl)phenyl)-2-chloropropionamide; 937604-58-5; Propanamide, N-[3,5-bis(trifluoromethyl)phenyl]-2-chloro-
EINECS	Contact for details

Quality Control

Our production of n-(3,5-Bis(Trifluoromethyl)Phenyl)-2-Chloropropanamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.