Description

3-Cyano-5-Fluorobenzeneboronic Acid Pinacol Ester, 96% is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to create biaryl structures, a common motif in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing fluorinated and cyanated aromatic systems.
• Agrochemical Research: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Organic Electronic Materials: A building block for synthesizing conjugated polymers and small molecules used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and target engagement.

Basic Information

Item	Details
Product Name	3-Cyano-5-Fluorobenzeneboronic Acid Pinacol Ester, 96%
CAS No.	935685-88-4
Molecular Formula	C₁₃H₁₅BFNO₂
Molecular Weight	247.08 g/mol
Synonyms	5-Fluoro-3-cyanophenylboronic acid pinacol ester; (5-Fluoro-3-cyanophenyl)boronic acid pinacol ester; 3-Cyano-5-fluorophenylboronic acid pinacol ester; 2-(5-Fluoro-3-cyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; PINACOL (5-FLUORO-3-CYANOPHENYL)BORONATE; (3-Cyano-5-fluorophenyl)boronic acid pinacol ester; CAS 935685-88-4
EINECS	Contact for details

Quality Control

Our 3-Cyano-5-Fluorobenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.