Description

1-Bromo-4-Fluoro-2-Methoxy-5-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments due to its nitro and methoxy substituents.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling the introduction of the bromo-fluoro-methoxy-nitro-phenyl moiety into more complex architectures.

Basic Information

Product Name	1-Bromo-4-Fluoro-2-Methoxy-5-Nitrobenzene
CAS No.	935288-20-3
Molecular Formula	C7H5BrFNO3
Molecular Weight	250.02 g/mol
Synonyms	2-Bromo-5-fluoro-4-methoxy-1-nitrobenzene; 4-Bromo-1-fluoro-2-methoxy-5-nitrobenzene; 5-Bromo-2-fluoro-4-methoxy-1-nitrobenzene; 1-Bromo-4-fluoro-2-methoxy-5-nitro-benzene; Benzene, 1-bromo-4-fluoro-2-methoxy-5-nitro-
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-4-Fluoro-2-Methoxy-5-Nitrobenzene adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.