Description

3,3-Difluoro-Piperidin-1-Ylamine is a high-purity, fluorinated piperidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique chemical structure, which introduces both fluorine atoms and a reactive amine group, enabling precise modifications to the core pharmacophore in drug discovery. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro motif can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced materials with tailored surface properties.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	3,3-Difluoro-Piperidin-1-Ylamine
CAS No.	935260-59-6
Molecular Formula	C5H10F2N2
Molecular Weight	136.14 g/mol
Synonyms	1-Amino-3,3-difluoropiperidine; 3,3-Difluoropiperidin-1-amine; 3,3-Difluoro-1-piperidinamine; 1-Piperidinamine, 3,3-difluoro-; 3,3-Difluoropiperidin-1-ylamine; 3,3-Difluoro-1-aminopiperidine; 3,3-Difluoropiperidine-1-amine
EINECS	Contact for details

Quality Control

Our 3,3-Difluoro-Piperidin-1-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and documentation traceability supports our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.