Description

1-Difluoromethoxy-4-Nitro-2-Trifluoromethyl-Benzene is a high-value fluorinated aromatic building block, essential for introducing multiple fluorine-containing functional groups into complex molecular architectures. This compound is critical for researchers and manufacturers requiring precise structural motifs to modulate the physicochemical properties of advanced materials and active pharmaceutical ingredients. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, crop protection, and the synthesis of novel electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing lipophilic and metabolically stable difluoromethoxy and trifluoromethyl groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorinated groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials that benefit from fluorine's unique properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
• Fluorine Chemistry Studies: An important reagent for studying structure-activity relationships (SAR) and the effects of polyfluorination on molecular behavior.

Basic Information

Product Name	1-Difluoromethoxy-4-Nitro-2-Trifluoromethyl-Benzene
CAS No.	933674-83-0
Molecular Formula	C9H4F5NO3
Molecular Weight	269.13 g/mol
Synonyms	4-Nitro-2-(trifluoromethyl)-1-(difluoromethoxy)benzene; Benzene, 1-(difluoromethoxy)-4-nitro-2-(trifluoromethyl)-; 2-Trifluoromethyl-4-nitro-1-difluoromethoxybenzene; 1-Difluoromethoxy-4-nitro-2-trifluoromethylbenzene; α,α-Difluoro-4-nitro-2-trifluoromethylanisole
EINECS	Contact for details

Quality Control

Every batch of 1-Difluoromethoxy-4-Nitro-2-Trifluoromethyl-Benzene is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.