Description

2-Bromo-2-(trifluoromethyl)difluorooxirane is a specialized fluorinated oxirane derivative, a high-value building block in advanced chemical synthesis. Its unique structure, featuring bromine and multiple fluorine substituents, makes it a critical reagent for introducing trifluoromethyl and difluorooxirane motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in protease inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides with improved environmental profiles.
• Fluorinated Material Precursor: Serves as a building block for specialty polymers and coatings with unique oil, water, and chemical resistance.
• Organic Synthesis Reagent: Employed in cycloaddition and ring-opening reactions to construct complex, fluorinated heterocycles.
• Ligand and Catalyst Development: Useful in creating novel fluorinated ligands for asymmetric catalysis and material science.
• R&D and Process Chemistry: A valuable tool for medicinal and process chemists exploring structure-activity relationships (SAR) in discovery programs.

Basic Information

Item	Details
Product Name	2-Bromo-2-(trifluoromethyl)difluorooxirane
CAS No.	933668-42-9
Molecular Formula	C3BrF5O
Molecular Weight	226.93 g/mol
Synonyms	2-Bromo-2-(trifluoromethyl)-2,2-difluorooxirane; 3-Bromo-3-(trifluoromethyl)-3,3-difluorooxirane; Bromo(trifluoromethyl)difluorooxirane; Oxirane, 2-bromo-2-(trifluoromethyl)-2,2-difluoro-; Difluoro(trifluoromethyl)bromooxirane
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-(trifluoromethyl)difluorooxirane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 19F) and chromatographic methods (GC/HPLC), to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.